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Centrifuge Solution for Monoclonal Antibody Discovery
Centrifugation is part of all mAb workflow steps! Eppendorf‘s Centrifuge Solutions keep up with all demands – compiled to fit highly specific needs of each step, method and sample type. Cope efficiently with various vessel formats, volumes and repetitive centrifugation steps. Master high-throughput and cell culture applications. Handle temperature-sensitive and valuable samples safely and reproducibly. Minimize interaction periods with fast and easy to handle devices and keep processes running. From hit generation and screening up to transfer to production - our solutions are made for optimal centrifugation to produce fast and reliable results!
Discover the centrifuge workflow solutions
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Hit to Lead Discovery
Production of Target Antigen
MOLECULAR BIOLOGY SOLUTION
Plasmid construction (small) | Sequencing preparation | Humanization (small)
- Safe centrifugation with open tube lids
- Fast and easy operation: QuickLock® rotor, short key function, automatic lid opening
- Minimal noise pollution: optimized sound design
HIGH SPEED SOLUTION
Plasmid construction (large) | Lysate clarification | Humanization (large)
- Fast and easy operation: favorite functions accessible within seconds, QuickLock® rotor
- Optimal cooling for sample integrity
BIG VOLUME HARVESTING SOLUTION
Expression in bacteria and cell lines | Antibody expression
- For large volume suspensions
- Optimal cooling for cell integrity
- Cross-contamination risk reduction
- GxP documentation support
VERSATILITY SOLUTION
Antigen concentration | Hybridoma technology | PBMC isolation | FACS/Flow cytometry
- For various vessel formats
- Optimal cooling for temperature-sensitive samples
- Optimized deceleration ramps
- Fast and reproducible operation
Generation of Hits and Identification
VERSATILITY SOLUTION
Antigen concentration | Hybridoma technology | PBMC isolation | FACS/Flow cytometry
- For various vessel formats
- Optimal cooling for temperature-sensitive samples
- Optimized deceleration ramps
- Fast and reproducible operation
HIGH-THROUGHPUT SCREENING SOLUTION
High-throughput screeing
- Easy and safe plate handling: high-capacity plate carrier, closed plate buckets
- Fast operation: automated, quick pre-cooling
Characterization of Hits and Selection of Leads
VERSATILITY SOLUTION
Antigen concentration | Hybridoma technology | PBMC isolation | FACS/Flow cytometry
- For various vessel formats
- Optimal cooling for temperature-sensitive samples
- Optimized deceleration ramps
- Fast and reproducible operation
LOW-THROUGHPUT SCREENING SOLUTION
Screening assays | Sequencing (spin down)
- Space saving: very small footprint
- Fast parameter changes
- Easy and safe operation: Fast access to your most frequently used settings, automatic lid opening
Lead Optimization
Characterization of Leads
VERSATILITY SOLUTION
Antigen concentration | Hybridoma technology | PBMC isolation | FACS/Flow cytometry
- For various vessel formats
- Optimal cooling for temperature-sensitive samples
- Optimized deceleration ramps
- Fast and reproducible operation
LOW-THROUGHPUT SCREENING SOLUTION
Screening assays | Sequencing (spin down)
- Space saving: very small footprint
- Fast parameter changes
- Easy and safe operation: Fast access to your most frequently used settings, automatic lid opening
MOLECULAR BIOLOGY SOLUTION
Plasmid construction (small) | Sequencing preparation | Humanization (small)
- Safe centrifugation with open tube lids
- Fast and easy operation: QuickLock® rotor, short key function, automatic lid opening
- Minimal noise pollution: optimized sound design
Protein Engineering of Antibody Leads
MOLECULAR BIOLOGY SOLUTION
Plasmid construction (small) | Sequencing preparation | Humanization (small)
- Safe centrifugation with open tube lids
- Fast and easy operation: QuickLock® rotor, short key function, automatic lid opening
- Minimal noise pollution: optimized sound design
HIGH SPEED SOLUTION
Plasmid construction (large) | Lysate clarification | Humanization (large)
- Fast and easy operation: favorite functions accessible within seconds, QuickLock® rotor
- Optimal cooling for sample integrity
Transient Antibody Leads Expression
BIG VOLUME HARVESTING SOLUTION
Expression in bacteria and cell lines | Antibody expression
- For large volume suspensions
- Optimal cooling for cell integrity
- Cross-contamination risk reduction
- GxP documentation support
Candidate Validation
In Vitro Validation
VERSATILITY SOLUTION
Antigen concentration | Hybridoma technology | PBMC isolation | FACS/Flow cytometry
- For various vessel formats
- Optimal cooling for temperature-sensitive samples
- Optimized deceleration ramps
- Fast and reproducible operation
LOW-THROUGHPUT SCREENING SOLUTION
Screening assays | Sequencing (spin down)
- Space saving: very small footprint
- Fast parameter changes
- Easy and safe operation: Fast access to your most frequently used settings, automatic lid opening
Cell Line Development
Classic Cell Culture Solution
Establishment of stable cell line
- Small footprint: optimal size to capacity ratio
- Sample & cross contamination risk reduction: aerosol-tight bucket caps
- Optimal ergonomics with low access height and soft touch lid
Centrifuge Service
Guarantee a safe working environment by regular maintenance as part of your quality management, and ensure that technical specifications comply with the manufacturer's specifications. With our maintenance,, calibration and qualification services, including GxP compliant documentation, you assure consistent instrument performance and safety and you are well prepared for audits.
Request your individual support
Request your individual support
Your own dedicated expert assists you in finding the perfect match for your specific mAb workflow. Get your individual consultation!
Read more
Read less